Reye syndrome

Also known as: Reye's syndrome

Acute encephalopathy with fatty liver after viral illness and aspirin use.

Medical specialty: Pediatrics
Subspecialty: Pediatrics / Pediatric critical care
Sex & age distribution: Male: affected; Female: affected, equal; Children: yes, usually under 15 years
Gene(s) involved: ACADM, CPT2

Etiology & mechanism

Mitochondrial injury with hyperammonemia and cerebral edema.

Gene(s) involved (2)

ACADMCPT2

Symptoms & signs (7)

comaconfusionhepatomegalyhypoglycemialethargyseizuresvomiting

SyndromeScope — educational reference. Content is model-generated and not clinically verified; always confirm against OMIM, Orphanet and GeneReviews before clinical use.