Presumed ocular histoplasmosis syndrome

Also known as: POHS

Chorioretinal scars with peripapillary atrophy and risk of choroidal neovascularization.

Medical specialty: Ophthalmology
Subspecialty: Ophthalmology / Uveitis
Sex & age distribution: Male: affected; Female: affected; Children: rare
Gene(s) involved: HLA-B7

Etiology & mechanism

Probable choroidal infection by Histoplasma capsulatum spores.

Gene(s) involved (1)

HLA-B7

Symptoms & signs (4)

central scotomametamorphopsiaperipapillary atrophypunched-out chorioretinal scars

SyndromeScope — educational reference. Content is model-generated and not clinically verified; always confirm against OMIM, Orphanet and GeneReviews before clinical use.