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Syndrome reference sheet
Generated 12 Oct 2026
Obstetrics and Gynecology · Obstetrics and Gynecology / Reproductive medicine

Premenstrual syndrome

Also known as: PMS

Cyclic physical and emotional symptoms before menses.

Medical specialty
Obstetrics and Gynecology
Subspecialty
Obstetrics and Gynecology / Reproductive medicine
Sex & age distribution
Male: not affected; Female: affected; Children: yes, adolescents
Gene(s) involved
ESR1

Etiology & mechanism

Hormone-neurotransmitter sensitivity.

Gene(s) involved (1)

ESR1

Symptoms & signs (6)

bloatingbreast tendernessfatigueheadacheirritabilitymood swings
SyndromeScope — educational reference. Content is model-generated and not clinically verified; always confirm against OMIM, Orphanet and GeneReviews before clinical use.