Pentalogy of Cantrell

Also known as: Cantrell syndrome

Midline defects: omphalocele, sternal cleft, diaphragmatic, pericardial and cardiac anomalies.

Medical specialty: Cardiology
Subspecialty: Cardiology / Congenital heart disease
Sex & age distribution: Male: affected, more common; Female: affected; Children: yes, neonatal
Gene(s) involved: None recorded

Etiology & mechanism

Early embryonic midline mesoderm defect.

Gene(s) involved (0)

No gene recorded.

Symptoms & signs (7)

cleft sternumdiaphragmatic herniaectopia cordisheart defectsomphalocelepericardial defectrespiratory distress

SyndromeScope — educational reference. Content is model-generated and not clinically verified; always confirm against OMIM, Orphanet and GeneReviews before clinical use.