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Syndrome reference sheet
Generated 13 Oct 2026
Ophthalmology · Ophthalmology / Orbit and oculoplastics

Orbital apex syndrome

Also known as: Jacod syndrome; Rollet syndrome

Superior orbital fissure syndrome plus optic neuropathy.

Medical specialty
Ophthalmology
Subspecialty
Ophthalmology / Orbit and oculoplastics
Sex & age distribution
Male: affected; Female: affected; Children: yes
Gene(s) involved
None recorded

Etiology & mechanism

Lesion at the orbital apex involving the optic nerve and cranial nerves.

Gene(s) involved (0)

No gene recorded.

Symptoms & signs (5)

ophthalmoplegiapainproptosisptosisvision loss
SyndromeScope — educational reference. Content is model-generated and not clinically verified; always confirm against OMIM, Orphanet and GeneReviews before clinical use.