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Syndrome reference sheet
Generated 13 Oct 2026
Ophthalmology · Ophthalmology / Orbit and oculoplastics Orbital apex syndrome
Also known as: Jacod syndrome; Rollet syndrome
Superior orbital fissure syndrome plus optic neuropathy.
- Medical specialty
- Ophthalmology
- Subspecialty
- Ophthalmology / Orbit and oculoplastics
- Sex & age distribution
- Male: affected; Female: affected; Children: yes
- Gene(s) involved
- None recorded
Etiology & mechanism
Lesion at the orbital apex involving the optic nerve and cranial nerves.
Gene(s) involved (0)
No gene recorded.
Symptoms & signs (5)
ophthalmoplegiapainproptosisptosisvision loss