Neurofibromatosis type 2

Also known as: NF2-related schwannomatosis

Autosomal dominant tumor predisposition.

Medical specialty: Neurology
Subspecialty: Neurology / Neurocutaneous disorders
Sex & age distribution: Male: affected; Female: affected equally; Children: yes, severe form with early onset
Gene(s) involved: LZTR1, NF2, SMARCB1

Etiology & mechanism

NF2 loss.

Gene(s) involved (3)

LZTR1NF2SMARCB1

Symptoms & signs (5)

bilateral vestibular schwannomashearing lossimbalancemeningiomastinnitus

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