Neonatal lupus syndrome

Also known as: Neonatal lupus

Passive transfer of anti-Ro/La antibodies causing heart block and rash.

Medical specialty: Rheumatology
Subspecialty: Rheumatology / Autoimmune connective tissue disease
Sex & age distribution: Male: affected; Female: affected; Children: yes, neonates
Gene(s) involved: None recorded

Etiology & mechanism

Transplacental autoantibodies.

Gene(s) involved (0)

No gene recorded.

Symptoms & signs (4)

annular rashcongenital heart blockcytopeniasliver involvement

SyndromeScope — educational reference. Content is model-generated and not clinically verified; always confirm against OMIM, Orphanet and GeneReviews before clinical use.