Neonatal abstinence syndrome

Also known as: NAS

Withdrawal symptoms in newborns after prenatal opioid exposure.

Medical specialty: Psychiatry
Subspecialty: Psychiatry / Substance use disorders
Sex & age distribution: Male: affected; Female: affected; Children: yes, neonatal
Gene(s) involved: COMT, OPRM1

Etiology & mechanism

Abrupt cessation of in utero opioid exposure.

Gene(s) involved (2)

COMTOPRM1

Symptoms & signs (7)

diarrheahigh-pitched cryirritabilitypoor feedingseizuressweatingtremor

SyndromeScope — educational reference. Content is model-generated and not clinically verified; always confirm against OMIM, Orphanet and GeneReviews before clinical use.