Myelodysplastic syndrome

Also known as: MDS

Clonal marrow disorders with ineffective hematopoiesis.

Medical specialty: Oncology
Subspecialty: Oncology / Hematologic malignancies
Sex & age distribution: Male: affected, male predominance; Female: affected; Children: rare
Gene(s) involved: ASXL1, DNMT3A, RUNX1, SF3B1, SRSF2, TET2, TP53

Etiology & mechanism

Clonal hematopoietic stem cell mutations.

Gene(s) involved (7)

ASXL1DNMT3ARUNX1SF3B1SRSF2TET2TP53

Symptoms & signs (6)

anemiableedingbruisingfatigueinfectionsprogression to aml

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