Microscopic colitis syndrome

Also known as: Collagenous and lymphocytic colitis

Chronic watery diarrhea with normal colonoscopy and characteristic histology.

Medical specialty: Gastroenterology
Subspecialty: Gastroenterology / Inflammatory bowel disease
Sex & age distribution: Male: affected; Female: affected, 3–5:1 female predominance; Children: rare
Gene(s) involved: HLA-DQ2, HLA-DQ8

Etiology & mechanism

Immune-mediated colonic inflammation.

Gene(s) involved (2)

HLA-DQ2HLA-DQ8

Symptoms & signs (5)

abdominal painchronic watery diarrheanocturnal diarrheaurgencyweight loss

SyndromeScope — educational reference. Content is model-generated and not clinically verified; always confirm against OMIM, Orphanet and GeneReviews before clinical use.