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Syndrome reference sheet
Generated 12 Oct 2026
ENT · ENT / Otology and neurotology

Meniere syndrome

Also known as: Endolymphatic hydrops; Ménière disease

Episodic vertigo with fluctuating hearing loss, tinnitus and aural fullness.

Medical specialty
ENT
Subspecialty
ENT / Otology and neurotology
Sex & age distribution
Male: affected; Female: affected, slight female predominance; Children: rare, peak 40–60 years
Gene(s) involved
COCH, DTNA, FAM136A, PRKCB, SEMA3D

Etiology & mechanism

Endolymphatic hydrops of the inner ear.

Gene(s) involved (5)

COCHDTNAFAM136APRKCBSEMA3D

Symptoms & signs (6)

aural fullnessepisodic vertigolow-frequency hearing lossnauseatinnitusvomiting
SyndromeScope — educational reference. Content is model-generated and not clinically verified; always confirm against OMIM, Orphanet and GeneReviews before clinical use.