Melkersson–Rosenthal syndrome

Also known as: Orofacial granulomatosis

Recurrent orofacial swelling, facial palsy and fissured tongue.

Medical specialty: Dentistry
Subspecialty: Dentistry / Oral medicine
Sex & age distribution: Male: affected; Female: affected, female predominance; Children: yes, young adults
Gene(s) involved: FOXP3

Etiology & mechanism

Granulomatous inflammation.

Gene(s) involved (1)

FOXP3

Symptoms & signs (3)

facial palsyfissured tonguelip swelling

SyndromeScope — educational reference. Content is model-generated and not clinically verified; always confirm against OMIM, Orphanet and GeneReviews before clinical use.