McLeod syndrome

Also known as: McLeod neuroacanthocytosis syndrome

X-linked disorder with weak Kell antigen expression, chorea and myopathy.

Medical specialty: Neurology
Subspecialty: Neurology / Movement disorders; Hematology
Sex & age distribution: Male: affected (X-linked); Female: carriers mildly affected; Children: rare, onset 30–40 years
Gene(s) involved: XK

Etiology & mechanism

Loss of XK protein.

Gene(s) involved (1)

Symptoms & signs (5)

cardiomyopathychoreacognitive and psychiatric changeelevated ckneuropathy

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