Mast cell activation syndrome

Also known as: MCAS

Episodic multisystem mast cell mediator release.

Medical specialty: Immunology
Subspecialty: Immunology / Allergy
Sex & age distribution: Male: affected; Female: affected, female predominance; Children: rare
Gene(s) involved: KIT

Etiology & mechanism

Mast cell hyperreactivity.

Gene(s) involved (1)

KIT

Symptoms & signs (5)

abdominal crampingflushinghiveshypotensionpalpitations

SyndromeScope — educational reference. Content is model-generated and not clinically verified; always confirm against OMIM, Orphanet and GeneReviews before clinical use.