Marchiafava–Bignami disease

Also known as: Marchiafava–Bignami syndrome

Corpus callosum demyelination and necrosis.

Medical specialty: Neurology
Subspecialty: Neurology / Nutritional neurology; Toxicology
Sex & age distribution: Male: affected, more common; Female: affected; Children: no, middle-aged and elderly
Gene(s) involved: None recorded

Etiology & mechanism

Chronic alcohol use and malnutrition.

Gene(s) involved (0)

No gene recorded.

Symptoms & signs (4)

dementiadisconnection signsdysarthriaseizures

SyndromeScope — educational reference. Content is model-generated and not clinically verified; always confirm against OMIM, Orphanet and GeneReviews before clinical use.