Lymphedema–distichiasis syndrome

Also known as: Lymphedema distichiasis

Late-onset lymphedema with extra eyelashes.

Medical specialty: Hematology
Subspecialty: Hematology / Lymphatic disorders
Sex & age distribution: Male: affected; Female: affected equally; Children: yes, puberty
Gene(s) involved: FOXC2

Etiology & mechanism

FOXC2 haploinsufficiency.

Gene(s) involved (1)

FOXC2

Symptoms & signs (5)

cleft palatedistichiasislower limb lymphedemaptosisvaricose veins

SyndromeScope — educational reference. Content is model-generated and not clinically verified; always confirm against OMIM, Orphanet and GeneReviews before clinical use.