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Syndrome reference sheet
Generated 12 Oct 2026
Gastroenterology · Gastroenterology / Hepatology

Lucey–Driscoll syndrome

Also known as: Transient familial neonatal hyperbilirubinemia

Transient severe neonatal jaundice from a maternal serum inhibitor.

Medical specialty
Gastroenterology
Subspecialty
Gastroenterology / Hepatology
Sex & age distribution
Male: affected; Female: affected, equal; Children: yes, neonatal
Gene(s) involved
None recorded

Etiology & mechanism

Inhibition of UGT1A1 by circulating maternal steroids.

Gene(s) involved (0)

No gene recorded.

Symptoms & signs (4)

kernicteruslethargyneonatal jaundicepoor feeding
SyndromeScope — educational reference. Content is model-generated and not clinically verified; always confirm against OMIM, Orphanet and GeneReviews before clinical use.