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Syndrome reference sheet
Generated 12 Oct 2026
Oncology · Oncology / Paraneoplastic syndromes

Leser–Trélat syndrome

Also known as: Sudden eruptive seborrheic keratoses

Sudden eruption of seborrheic keratoses with internal malignancy.

Medical specialty
Oncology
Subspecialty
Oncology / Paraneoplastic syndromes
Sex & age distribution
Male: affected; Female: affected; Children: no
Gene(s) involved
None recorded

Etiology & mechanism

Tumor growth factor secretion.

Gene(s) involved (0)

No gene recorded.

Symptoms & signs (4)

associated adenocarcinomapruritussudden numerous seborrheic keratosesweight loss
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