Lady Windermere syndrome

Also known as: Middle lobe syndrome with MAC

Nontuberculous mycobacterial infection of the right middle lobe and lingula in older women.

Medical specialty: Pulmonology
Subspecialty: Pulmonology / Infectious lung disease
Sex & age distribution: Male: rare; Female: affected, postmenopausal women; Children: no
Gene(s) involved: CFTR

Etiology & mechanism

Mycobacterium avium complex infection with ineffective secretion clearance.

Gene(s) involved (1)

CFTR

Symptoms & signs (5)

bronchiectasischronic coughfatiguehemoptysisweight loss

SyndromeScope — educational reference. Content is model-generated and not clinically verified; always confirm against OMIM, Orphanet and GeneReviews before clinical use.