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Syndrome reference sheet
Generated 13 Oct 2026
Cardiology · Cardiology / Coronary artery disease

Kounis syndrome

Also known as: Allergic angina; allergic myocardial infarction

Acute coronary syndrome triggered by allergic or hypersensitivity reactions.

Medical specialty
Cardiology
Subspecialty
Cardiology / Coronary artery disease
Sex & age distribution
Male: affected; Female: affected; Children: yes, rare
Gene(s) involved
None recorded

Etiology & mechanism

Mast cell activation releases mediators causing coronary vasospasm or plaque rupture.

Gene(s) involved (0)

No gene recorded.

Symptoms & signs (7)

chest paindyspneaflushinghypotensionpalpitationsst elevation after allergen or drug exposureurticaria
SyndromeScope — educational reference. Content is model-generated and not clinically verified; always confirm against OMIM, Orphanet and GeneReviews before clinical use.