Kernicterus syndrome

Also known as: Bilirubin encephalopathy

Bilirubin deposition in basal ganglia causing neurologic injury.

Medical specialty: Pediatrics
Subspecialty: Pediatrics / Neonatology
Sex & age distribution: Male: affected; Female: affected; Children: yes, neonates
Gene(s) involved: G6PD, UGT1A1

Etiology & mechanism

Severe unconjugated hyperbilirubinemia.

Gene(s) involved (2)

G6PDUGT1A1

Symptoms & signs (7)

athetosishearing losshigh-pitched cryjaundicelethargyopisthotonusupward gaze palsy

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