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Syndrome reference sheet
Generated 12 Oct 2026
Infectious Disease · Infectious disease / Bacterial infections Jarisch–Herxheimer reaction syndrome
Also known as: JHR
Fever and rigors after antibiotic treatment of spirochetal infection.
- Medical specialty
- Infectious Disease
- Subspecialty
- Infectious disease / Bacterial infections
- Sex & age distribution
- Male: affected; Female: affected; Children: yes
- Gene(s) involved
- None recorded
Etiology & mechanism
Cytokine release from dying spirochetes.
Gene(s) involved (0)
No gene recorded.
Symptoms & signs (5)
feverheadachehypotensionmyalgiarigors