Immune reconstitution inflammatory syndrome affecting CNS

Also known as: CNS-IRIS

Paradoxical inflammatory worsening after immune recovery.

Medical specialty: Neurology
Subspecialty: Neurology / Infectious neurology
Sex & age distribution: Male: affected; Female: affected; Children: yes, in HIV-infected children
Gene(s) involved: None recorded

Etiology & mechanism

Immune reconstitution with latent pathogens.

Gene(s) involved (0)

No gene recorded.

Symptoms & signs (4)

headachemass effectseizuresworsening neurologic deficits

SyndromeScope — educational reference. Content is model-generated and not clinically verified; always confirm against OMIM, Orphanet and GeneReviews before clinical use.