Immune reconstitution inflammatory syndrome

Also known as: IRIS

Paradoxical worsening of infection after starting antiretroviral therapy.

Medical specialty: Infectious Disease
Subspecialty: Infectious disease / Viral infections
Sex & age distribution: Male: affected; Female: affected; Children: yes
Gene(s) involved: HLA-B44, IL6

Etiology & mechanism

Restored immune response against pathogens.

Gene(s) involved (2)

HLA-B44IL6

Symptoms & signs (3)

feverparadoxical worsening of tb or cryptococcosisworsening lymphadenopathy

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