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Syndrome reference sheet
Generated 13 Oct 2026
Hematology · Hematology / Myeloid neoplasms

Hypereosinophilic syndrome

Also known as: HES

Persistent eosinophilia with organ damage.

Medical specialty
Hematology
Subspecialty
Hematology / Myeloid neoplasms
Sex & age distribution
Male: affected; Female: affected; Children: rare
Gene(s) involved
FIP1L1-PDGFRA

Etiology & mechanism

FIP1L1-PDGFRA or idiopathic.

Gene(s) involved (1)

FIP1L1-PDGFRA

Symptoms & signs (7)

cougheosinophiliafatigueheart failureneuropathyrashthrombosis
SyndromeScope — educational reference. Content is model-generated and not clinically verified; always confirm against OMIM, Orphanet and GeneReviews before clinical use.