Heyde syndrome

Also known as: Aortic stenosis with gastrointestinal angiodysplasia

Aortic stenosis with bleeding gastrointestinal angiodysplasia from acquired von Willebrand syndrome.

Medical specialty: Cardiology
Subspecialty: Cardiology / Valvular heart disease
Sex & age distribution: Male: affected; Female: affected equally; Children: no, elderly
Gene(s) involved: None recorded

Etiology & mechanism

Shear stress cleaves von Willebrand factor multimers.

Gene(s) involved (0)

No gene recorded.

Symptoms & signs (7)

anginaejection murmurexertional dyspneagastrointestinal bleedingiron deficiency anemiamelenasyncope

SyndromeScope — educational reference. Content is model-generated and not clinically verified; always confirm against OMIM, Orphanet and GeneReviews before clinical use.