Henoch–Schönlein purpura syndrome

Also known as: IgA vasculitis

IgA-mediated small-vessel vasculitis in children.

Medical specialty: Pediatrics
Subspecialty: Pediatrics / Pediatric rheumatology
Sex & age distribution: Male: affected, slight male predominance; Female: affected; Children: yes, 3–10 years
Gene(s) involved: HLA-DRB1*01, IL1B, MEFV

Etiology & mechanism

Immune complex deposition after infection.

Gene(s) involved (3)

HLA-DRB1*01IL1BMEFV

Symptoms & signs (6)

abdominal painarthralgiagastrointestinal bleedinghematurianephritispalpable purpura

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