Guillain–Barré syndrome

Also known as: GBS; Landry–Guillain–Barré–Strohl syndrome

Acute immune-mediated polyradiculoneuropathy with ascending weakness and areflexia.

Medical specialty: Neurology
Subspecialty: Neurology / Neuromuscular; Neuroimmunology
Sex & age distribution: Male: slightly more common; Female: affected; Children: yes, any age
Gene(s) involved: None recorded

Etiology & mechanism

Post-infectious molecular mimicry with antiganglioside antibodies.

Gene(s) involved (0)

No gene recorded.

Symptoms & signs (7)

areflexiaautonomic instabilityback painfacial weaknessparesthesiasrespiratory failuresymmetric ascending weakness

Note

Umbrella for #148–152, #441, #594–597, #771, #852, #853

SyndromeScope — educational reference. Content is model-generated and not clinically verified; always confirm against OMIM, Orphanet and GeneReviews before clinical use.