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Syndrome reference sheet
Generated 13 Oct 2026
Neurology · Neurology / Neuromuscular

Flail leg syndrome

Also known as: Pseudopolyneuritic ALS

ALS variant with predominant leg weakness.

Medical specialty
Neurology
Subspecialty
Neurology / Neuromuscular
Sex & age distribution
Male: affected, predominantly men; Female: affected; Children: no
Gene(s) involved
None recorded

Etiology & mechanism

Motor neuron degeneration.

Gene(s) involved (0)

No gene recorded.

Symptoms & signs (2)

distal leg weaknessfoot drop
SyndromeScope — educational reference. Content is model-generated and not clinically verified; always confirm against OMIM, Orphanet and GeneReviews before clinical use.