Flail arm syndrome

Also known as: Brachial amyotrophic diplegia

ALS variant with predominant proximal arm weakness.

Medical specialty: Neurology
Subspecialty: Neurology / Neuromuscular
Sex & age distribution: Male: affected, predominantly men; Female: affected; Children: no, adults
Gene(s) involved: FUS, SOD1, TARDBP

Etiology & mechanism

Motor neuron degeneration.

Gene(s) involved (3)

FUSSOD1TARDBP

Symptoms & signs (2)

proximal arm weaknessupper limb amyotrophy

SyndromeScope — educational reference. Content is model-generated and not clinically verified; always confirm against OMIM, Orphanet and GeneReviews before clinical use.