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Syndrome reference sheet
Generated 12 Oct 2026
ENT · ENT / Laryngology and head and neck

First bite syndrome

Also known as: Parapharyngeal space syndrome

Severe parotid pain with first bite after neck surgery.

Medical specialty
ENT
Subspecialty
ENT / Laryngology and head and neck
Sex & age distribution
Male: affected; Female: affected; Children: no
Gene(s) involved
None recorded

Etiology & mechanism

Sympathetic denervation of parotid myoepithelial cells.

Gene(s) involved (0)

No gene recorded.

Symptoms & signs (2)

parotid crampingsevere pain on first bite
SyndromeScope — educational reference. Content is model-generated and not clinically verified; always confirm against OMIM, Orphanet and GeneReviews before clinical use.