Fetal valproate syndrome

Also known as: Valproate embryopathy

Teratogenic effects of valproate in pregnancy.

Medical specialty: Pediatrics
Subspecialty: Pediatrics / Neonatology
Sex & age distribution: Male: affected; Female: affected; Children: yes, congenital
Gene(s) involved: None recorded

Etiology & mechanism

Histone deacetylase inhibition and folate antagonism.

Gene(s) involved (0)

No gene recorded.

Symptoms & signs (5)

autism riskdevelopmental delayfacial dysmorphismheart defectsneural tube defects

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