Fetal hydantoin syndrome

Also known as: Fetal phenytoin syndrome

Teratogenic effects of phenytoin exposure in utero.

Medical specialty: Pediatrics
Subspecialty: Pediatrics / Neonatology
Sex & age distribution: Male: affected; Female: affected; Children: yes, congenital
Gene(s) involved: EPHX1

Etiology & mechanism

Arene oxide metabolites causing teratogenesis.

Gene(s) involved (1)

EPHX1

Symptoms & signs (5)

cleft lip and palatedevelopmental delaygrowth restrictionmicrocephalynail hypoplasia

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