Familial atypical multiple mole melanoma syndrome

Also known as: FAMMM syndrome

Multiple atypical nevi with melanoma and pancreatic cancer risk.

Medical specialty: Oncology
Subspecialty: Oncology / Hereditary cancer syndromes
Sex & age distribution: Male: affected; Female: affected; Children: yes, adolescents
Gene(s) involved: BAP1, CDK4, CDKN2A, MITF, POT1

Etiology & mechanism

CDKN2A inactivation.

Gene(s) involved (5)

BAP1CDK4CDKN2AMITFPOT1

Symptoms & signs (4)

melanomanumerous atypical molespancreatic canceruveal melanoma

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