Eisenmenger syndrome

Also known as: Eisenmenger complex

Reversed shunt with cyanosis due to severe pulmonary vascular disease from a long-standing left-to-right shunt.

Medical specialty: Cardiology
Subspecialty: Cardiology / Congenital heart disease
Sex & age distribution: Male: affected; Female: affected, more common; Children: yes, adolescents and adults
Gene(s) involved: BMPR2

Etiology & mechanism

Chronic pulmonary overcirculation causes irreversible pulmonary vascular remodeling.

Gene(s) involved (1)

BMPR2

Symptoms & signs (9)

clubbingcyanosisdyspneafatiguehemoptysispolycythemiaright heart failurestrokesyncope

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