Edwards syndrome

Also known as: Trisomy 18

Trisomy 18 with severe malformations and early death.

Medical specialty: Pediatrics
Subspecialty: Pediatrics / Pediatric genetics
Sex & age distribution: Male: affected; Female: affected, 3:1 female predominance; Children: yes, usually death in first year
Gene(s) involved: None recorded

Etiology & mechanism

Extra copy of chromosome 18.

Gene(s) involved (0)

No gene recorded.

Symptoms & signs (6)

clenched hands with overlapping fingersgrowth restrictionheart defectsintellectual disabilitymicrognathiarocker-bottom feet

SyndromeScope — educational reference. Content is model-generated and not clinically verified; always confirm against OMIM, Orphanet and GeneReviews before clinical use.