Ectopic ACTH syndrome

Also known as: Paraneoplastic Cushing syndrome

Cushing syndrome caused by non-pituitary ACTH-secreting tumor.

Medical specialty: Endocrinology
Subspecialty: Endocrinology / Adrenal disorders
Sex & age distribution: Male: affected, more common; Female: affected; Children: rare
Gene(s) involved: None recorded

Etiology & mechanism

Ectopic ACTH from lung or neuroendocrine tumors.

Gene(s) involved (0)

No gene recorded.

Symptoms & signs (8)

diabeteshyperpigmentationhypertensionhypokalemiainfectionsproximal weaknesspsychosisrapid weight loss

SyndromeScope — educational reference. Content is model-generated and not clinically verified; always confirm against OMIM, Orphanet and GeneReviews before clinical use.