Doose syndrome

Also known as: Myoclonic-atonic epilepsy

Childhood epilepsy with myoclonic-atonic seizures.

Medical specialty: Neurology
Subspecialty: Neurology / Childhood seizure syndromes
Sex & age distribution: Male: affected, male predominance; Female: affected; Children: yes, onset 1–5 years
Gene(s) involved: SCN1A, SCN1B, SLC2A1, SLC6A1

Etiology & mechanism

Genetically heterogeneous generalized epilepsy.

Gene(s) involved (4)

SCN1ASCN1BSLC2A1SLC6A1

Symptoms & signs (4)

absencesatonic seizuresdrop attacksmyoclonic jerks

SyndromeScope — educational reference. Content is model-generated and not clinically verified; always confirm against OMIM, Orphanet and GeneReviews before clinical use.