Cyclic vomiting syndrome

Also known as: CVS

Recurrent stereotyped episodes of intense vomiting.

Medical specialty: Gastroenterology
Subspecialty: Gastroenterology / Functional GI disorders
Sex & age distribution: Male: affected; Female: affected, slight female predominance; Children: yes, typical onset at age 3–7
Gene(s) involved: DNA, RYR2

Etiology & mechanism

Gut-brain dysregulation linked to migraine and mitochondrial DNA variants.

Gene(s) involved (2)

DNARYR2

Symptoms & signs (7)

abdominal paindehydrationlethargynauseapallorphotophobiastereotyped vomiting episodes

SyndromeScope — educational reference. Content is model-generated and not clinically verified; always confirm against OMIM, Orphanet and GeneReviews before clinical use.