Cyclic neutropenia syndrome

Also known as: Cyclic hematopoiesis

Periodic oscillation of neutrophil counts about every 21 days.

Medical specialty: Hematology
Subspecialty: Hematology / Bone marrow failure
Sex & age distribution: Male: affected; Female: affected; Children: yes
Gene(s) involved: ELANE

Etiology & mechanism

ELANE variants.

Gene(s) involved (1)

ELANE

Symptoms & signs (5)

gingivitisneutropenia every 21 daysoral ulcersperiodic feverskin infections

SyndromeScope — educational reference. Content is model-generated and not clinically verified; always confirm against OMIM, Orphanet and GeneReviews before clinical use.