Conn syndrome

Also known as: Primary aldosteronism

Hypertension and hypokalemia from aldosterone excess.

Medical specialty: Endocrinology
Subspecialty: Endocrinology / Adrenal disorders
Sex & age distribution: Male: affected; Female: affected; Children: rare
Gene(s) involved: ATP1A1, ATP2B3, CACNA1D, CACNA1H, CLCN2, CTNNB1, CYP11B1, CYP11B2, KCNJ5

Etiology & mechanism

Aldosterone-producing adenoma or bilateral hyperplasia.

Gene(s) involved (9)

ATP1A1ATP2B3CACNA1DCACNA1HCLCN2CTNNB1CYP11B1CYP11B2KCNJ5

Symptoms & signs (8)

headachehypertensionhypokalemiamuscle weaknesspalpitationsparesthesiaspolydipsiapolyuria

SyndromeScope — educational reference. Content is model-generated and not clinically verified; always confirm against OMIM, Orphanet and GeneReviews before clinical use.