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Syndrome reference sheet
Generated 13 Oct 2026
Neurology · Neurology / Neuroimmunology

Clinically isolated syndrome

Also known as: CIS

First clinical demyelinating attack suggestive of MS.

Medical specialty
Neurology
Subspecialty
Neurology / Neuroimmunology
Sex & age distribution
Male: affected; Female: affected, more common; Children: yes, pediatric cases
Gene(s) involved
None recorded

Etiology & mechanism

Inflammatory demyelination.

Gene(s) involved (0)

No gene recorded.

Symptoms & signs (3)

brainstem syndromemyelitisoptic neuritis
SyndromeScope — educational reference. Content is model-generated and not clinically verified; always confirm against OMIM, Orphanet and GeneReviews before clinical use.