Chronic intestinal pseudo-obstruction syndrome

Also known as: CIPO

Recurrent obstruction symptoms without a mechanical cause.

Medical specialty: Gastroenterology
Subspecialty: Gastroenterology / Pediatric GI disease
Sex & age distribution: Male: affected; Female: affected, equal; Children: yes, neonatal or childhood onset
Gene(s) involved: ACTG2, FLNA, L1CAM, LMOD1, MMYBP, MYH11, RAD21, SOX10

Etiology & mechanism

Enteric neuromuscular dysfunction.

Gene(s) involved (8)

ACTG2FLNAL1CAMLMOD1MMYBPMYH11RAD21SOX10

Symptoms & signs (6)

abdominal distensionabdominal painbacterial overgrowthconstipationmalnutritionvomiting

SyndromeScope — educational reference. Content is model-generated and not clinically verified; always confirm against OMIM, Orphanet and GeneReviews before clinical use.