Budd–Chiari syndrome

Also known as: Hepatic vein outflow obstruction

Obstruction of hepatic venous outflow.

Medical specialty: Cardiology
Subspecialty: Cardiology / Vascular medicine
Sex & age distribution: Male: affected; Female: affected, slightly more; Children: rare
Gene(s) involved: F2, F5, JAK2

Etiology & mechanism

Thrombosis due to myeloproliferative disease or hypercoagulable states.

Gene(s) involved (3)

F2F5JAK2

Symptoms & signs (6)

abdominal painasciteshepatomegalyjaundiceliver failurevariceal bleeding

SyndromeScope — educational reference. Content is model-generated and not clinically verified; always confirm against OMIM, Orphanet and GeneReviews before clinical use.