Blue baby syndrome

Also known as: Methemoglobinemia in infants

Cyanosis from methemoglobin in infants.

Medical specialty: Pediatrics
Subspecialty: Pediatrics / Neonatology
Sex & age distribution: Male: affected; Female: affected; Children: yes, under 6 months
Gene(s) involved: CYB5R3, HBB

Etiology & mechanism

Nitrate-induced oxidation of hemoglobin.

Gene(s) involved (2)

CYB5R3HBB

Symptoms & signs (4)

chocolate-brown bloodcyanosislethargytachypnea

SyndromeScope — educational reference. Content is model-generated and not clinically verified; always confirm against OMIM, Orphanet and GeneReviews before clinical use.