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Syndrome reference sheet
Generated 12 Oct 2026
Neurology · Neurology / Neuro-oncology

Bing–Neel syndrome

Also known as: Bing–Neel

CNS involvement of Waldenström macroglobulinemia.

Medical specialty
Neurology
Subspecialty
Neurology / Neuro-oncology
Sex & age distribution
Male: affected, more common; Female: affected; Children: no
Gene(s) involved
MYD88

Etiology & mechanism

Lymphoplasmacytic infiltration.

Gene(s) involved (1)

MYD88

Symptoms & signs (3)

cognitive changecranial neuropathymotor deficits
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