Asperger syndrome with neurological comorbidity

Also known as: Asperger syndrome

Historical diagnosis now within autism spectrum disorder.

Medical specialty: Neurology
Subspecialty: Psychiatry / Neurodevelopmental disorders
Sex & age distribution: Male: affected, 4:1 male predominance; Female: affected, underdiagnosed; Children: yes, usually school-age diagnosis
Gene(s) involved: CHD8, SHANK3

Etiology & mechanism

Neurodevelopmental.

Gene(s) involved (2)

CHD8SHANK3

Symptoms & signs (3)

motor clumsinessrestricted interestssocial communication difficulty

Note

Not a neurologic syndrome; verify

SyndromeScope — educational reference. Content is model-generated and not clinically verified; always confirm against OMIM, Orphanet and GeneReviews before clinical use.