Acute fatty liver of pregnancy syndrome

Also known as: AFLP

Liver failure in late pregnancy from microvesicular steatosis.

Medical specialty: Obstetrics and Gynecology
Subspecialty: Obstetrics and Gynecology / Obstetric complications
Sex & age distribution: Male: not affected; Female: affected; Children: no
Gene(s) involved: HADHA

Etiology & mechanism

Fetal long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency.

Gene(s) involved (1)

HADHA

Symptoms & signs (7)

abdominal paincoagulopathyencephalopathyhypoglycemiajaundicenauseavomiting

SyndromeScope — educational reference. Content is model-generated and not clinically verified; always confirm against OMIM, Orphanet and GeneReviews before clinical use.