Acute chest syndrome

Also known as: Sickle cell acute chest syndrome

Pulmonary complication of sickle cell disease.

Medical specialty: Hematology
Subspecialty: Hematology / Hemoglobinopathies
Sex & age distribution: Male: affected; Female: affected; Children: yes
Gene(s) involved: HBB

Etiology & mechanism

Sickling in lung microvasculature, infection and fat embolism.

Gene(s) involved (1)

HBB

Symptoms & signs (5)

chest paincoughfeverhypoxianew infiltrate

SyndromeScope — educational reference. Content is model-generated and not clinically verified; always confirm against OMIM, Orphanet and GeneReviews before clinical use.